Clinical relevance

QuantiFERON Monitor (QFM) is an in vitro diagnostic test detecting interferon-γ (IFNγ) following incubation of heparinized whole blood with innate and adaptive immune response stimulants.

Product description

The assay is used to detect cell mediated immune response in immunosuppressed solid organ transplant patients.

QuantiFERON Monitor is intended for use in conjunction with risk assessment and other medical and diagnostic evaluations.

Benefits

• Assesses cell-mediated immune (CMI) response
• Provides nonpathogen-specific immune monitoring
• Complements pathogen-specific monitoring
• Aids in clinical management of solid organ transplant patients

Product description

QuantiFERON^® – CMV is a blood test that measures the immune response of CD8+ cells to CMV. The test requires the collection of three 1 mL blood samples in special antigen-coated sample tubes with subsequent ELISA analysis in the laboratory. The ELISA measures IFN gamma as a marker of a person’s ability to protect themselves against viral infection.

SSI Diagnostica distributes QuantiFERON^® CMV in Denmark, Iceland, Norway and Sweden on behalf of QIAGEN, which has developed and manufactured the test.

Benefits

• QFN CMV is the only commercial test for monitoring cellular immunity specific to CMV.
• QFN CMV is a simple test that only requires 3 x 1 mL blood samples with subsequent laboratory analysis.
• QFN CMV is a rapid test with results within 24 hours.
• QFN CMV can predict the likelihood of developing CMV disease and assist in the clinical and therapeutic treatment of transplant patients 

Clinical relevance

QuantiFERON^® TB-Gold Plus is an ELISA test for the detection of M. tuberculosis in immunocompetent individuals, for example, as part of infection detection, screening of high-risk groups, in special cases for the detection of active tuberculous disease and before treatment with immunosuppressive drugs. In the case of infection with M. tuberculosis, the immune response is predominantly cell mediated. In infected immunocompetent individuals, stimulation of blood with specific antigens (ESAT 6, CFP 10 and TB 7.7) will cause T lymphocytes to release the cytokine interferon gamma, which is detected by ELISA.

QuantiFERON-TB Gold Plus is the first TB blood test to receive certification under the European Union’s new In Vitro Diagnostic Medical Devices Regulation (IVDR).

Product description

QuantiFERON^® TB-Gold Plus consists of an ELISA kit and blood collection tubes, which can be ordered separately. For sampling, four blood collection tubes are used: 1x Nil; 2x TB Ag and 1x Mitogen. The tubes are delivered as a combined package or in bulk. In the laboratory, up to 58 tests can be performed per ELISA kit. SSI Diagnostica distributes QuantiFERON^®TB-Gold Plus in Denmark, Iceland, Norway and Sweden on behalf of QIAGEN.

Benefits

• Detection of infection with M. tuberculosis
• Result within 24 hours
• Distinguishes between infection with M. tuberculosis and BCG vaccination
• Can be easily repeated – no booster phenomenon
• Only one patient visit (compared to Mantoux test)
• High reproducibility
• Objective reading (95% CI 98-100%)
• >99% specificity and >89% (95% CI 83-93%) sensitivity